← Drug quick-reference

Sertraline

Brand: Zoloft

SSRI antidepressantUsed for: Depression, anxietyCNS & Psychiatric
Key warning

Boxed warning: suicidal thoughts and behaviors in children, adolescents, and young adults

Common side effects

  • Nausea
  • Diarrhea
  • Trouble sleeping
  • Sexual dysfunction
  • Headache

Key interactions & cautions

  • Risk of serotonin syndrome with other serotonergic drugs
  • Avoid MAO inhibitors
  • NSAIDs and blood thinners raise bleeding risk
  • Limit alcohol

Counseling points

  • May take a few weeks to work fully
  • Take at the same time each day
  • Do not stop suddenly
  • Report worsening mood or suicidal thoughts
  • Report agitation, fever, or muscle twitching

High-yield study aid for exam prep — not a substitute for the package insert or a pharmacist’s dispensing reference.