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Sumatriptan

Brand: Imitrex

TriptanUsed for: Acute migraineCNS & Psychiatric

No boxed warning on the current FDA label.

Caution
Contraindicated with coronary artery disease, uncontrolled hypertension, or prior stroke because it constricts blood vessels.

Common side effects

  • Chest tightness
  • Tingling or flushing
  • Dizziness
  • Fatigue
  • Injection-site reaction

Key interactions

  • Avoid within 24 hours of ergot medicines
  • Avoid MAO inhibitors
  • Serotonin syndrome risk with SSRIs or SNRIs
  • Do not use with other triptans same day

Counseling points

  • Take at first sign of migraine
  • Do not use for more than a few days weekly
  • Report chest pain or pressure
  • Avoid if you have heart disease
  • May repeat dose after 2 hours if needed
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