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Quetiapine

Brand: Seroquel

Atypical antipsychoticUsed for: Schizophrenia, bipolar disorderCNS & Psychiatric
Boxed warning

Increased mortality in elderly patients with dementia-related psychosis; suicidal thoughts and behaviors in young adults.

Caution
Metabolic changes (weight gain, high blood sugar, high lipids), sedation, and orthostatic hypotension.

Common side effects

  • Drowsiness
  • Dizziness
  • Weight gain
  • Dry mouth
  • Constipation

Key interactions

  • Alcohol increases sedation
  • Adds to other sedating drugs
  • Caution with blood-pressure medicines
  • Certain drugs affect its blood levels

Counseling points

  • Rise slowly to reduce dizziness
  • May take with or without food
  • Report high blood sugar symptoms
  • Do not stop suddenly
  • Monitor weight and blood sugar
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