Naproxen
Brand: Aleve, Naprosyn
Key warning
Boxed warning (prescription labels): serious cardiovascular thrombotic events and GI bleeding, ulceration and perforation. OTC naproxen carries no boxed warning — the same Rx/OTC split as ibuprofen.
Common side effects
- Stomach upset
- Heartburn
- Fluid retention
- Elevated blood pressure
Key interactions & cautions
- Adds bleeding risk with blood thinners
- May blunt blood-pressure medications
- Avoid combining with other NSAIDs
Counseling points
- Take with food or milk
- Report black or bloody stools
- Limit alcohol
- Use lowest dose for shortest time
- Stay hydrated
High-yield study aid for exam prep — not a substitute for the package insert or a pharmacist’s dispensing reference.