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Methylprednisolone

Brand: Medrol

CorticosteroidUsed for: InflammationEndocrine & Diabetes

No boxed warning on the current FDA label.

Caution
Adrenal suppression with prolonged use; raises blood sugar and infection risk.

Common side effects

  • Increased appetite
  • Insomnia
  • Mood changes
  • Elevated blood sugar
  • Fluid retention

Key interactions

  • NSAIDs increase stomach ulcer risk
  • May raise blood sugar with diabetes drugs
  • Live vaccines should be avoided

Counseling points

  • Take with food to reduce stomach upset
  • Do not stop suddenly; follow the taper
  • Report signs of infection
  • May raise blood sugar; monitor if diabetic
  • Take earlier in the day to reduce insomnia
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