Losartan
Brand: Cozaar
Boxed warning
Fetal toxicity: stop as soon as pregnancy is detected because it can injure or kill the developing fetus.
- Caution
- High potassium and kidney impairment, especially with potassium-sparing drugs or NSAIDs.
- Pregnancy
- Avoid in pregnancy: fetal toxicity (boxed); stop as soon as pregnancy is detected.
Common side effects
- Dizziness
- Elevated potassium
- Fatigue
- Low blood pressure
Key interactions
- NSAIDs blunt its blood-pressure effect
- Avoid potassium supplements and salt substitutes
- Caution with other blood-pressure drugs
- Watch kidney function with certain diuretics
Counseling points
- Take at the same time each day
- Rise slowly to reduce dizziness
- Report swelling of face or lips
- Limit high-potassium salt substitutes
- Keep up blood-pressure checks
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