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Glipizide

Brand: Glucotrol (discontinued), Glucotrol XL

SulfonylureaUsed for: Type 2 diabetesEndocrine & Diabetes

No boxed warning on the current FDA label. On the ISMP high-alert list.

Caution
Hypoglycemia, especially with skipped meals, alcohol, or kidney impairment.
Pregnancy
Usually switched to insulin in pregnancy.

Common side effects

  • Low blood sugar
  • Weight gain
  • Nausea
  • Dizziness

Key interactions

  • Adds to other glucose-lowering drugs
  • Alcohol raises low-blood-sugar risk
  • Beta blockers may mask low-sugar signs

Counseling points

  • Take about 30 minutes before breakfast
  • Recognize and treat low blood sugar
  • Do not skip meals
  • Carry a fast sugar source
  • Limit alcohol
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