Glimepiride
Brand: Amaryl
No boxed warning on the current FDA label. On the ISMP high-alert list.
- Caution
- Hypoglycemia, especially with skipped meals or kidney impairment; sulfonamide allergy caution.
- Pregnancy
- Usually switched to insulin in pregnancy.
Common side effects
- Low blood sugar
- Weight gain
- Nausea
- Dizziness
- Headache
Key interactions
- Alcohol can worsen low blood sugar
- Beta blockers may mask low-sugar signs
- Some drugs increase low-sugar risk
Counseling points
- Take with breakfast or first main meal
- Recognize and treat low blood sugar
- Do not skip meals after dosing
- Carry a fast sugar source
- Limit alcohol
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