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Gemfibrozil

Brand: Lopid

FibrateUsed for: High triglyceridesCardiovascular

No boxed warning on the current FDA label.

Caution
Contraindicated with simvastatin and with repaglinide; rhabdomyolysis risk with any statin.

Common side effects

  • Indigestion
  • Abdominal pain
  • Gallstones
  • Muscle aches

Key interactions

  • Must not be combined with simvastatin: high rhabdomyolysis risk
  • Raises the effect of warfarin
  • Raises repaglinide levels

Counseling points

  • Take 30 minutes before the morning and evening meal
  • Report muscle pain, tenderness, or dark urine
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