Fluconazole
Brand: Diflucan
No boxed warning on the current FDA label.
- Caution
- QT prolongation and liver injury; many CYP interactions.
- Storage
- Reconstituted suspension: room temperature or refrigerated, discard after 14 days.
- Pregnancy
- Avoid repeated or high doses (400 to 800 mg per day) in the first trimester: birth-defect risk; a single 150 mg dose is generally considered low risk.
Common side effects
- Nausea
- Headache
- Stomach pain
- Rash
Key interactions
- Raises levels of many drugs
- Increases warfarin bleeding risk
- Caution with statins
- Can affect heart rhythm with some drugs
Counseling points
- May take with or without food
- Finish the full course
- Report yellowing of skin or eyes
- Tell provider about all your medicines
- Report rash or blistering
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