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Erythromycin

Brand: Ery-Tab, E.E.S.

Macrolide antibioticUsed for: Respiratory and skin infectionsAnti-Infectives

No boxed warning on the current FDA label.

Caution
QT prolongation and many CYP3A4 interactions; GI upset is the most common side effect.

Common side effects

  • Stomach cramps and nausea
  • Diarrhea
  • QT prolongation
  • Altered taste

Key interactions

  • Moderate CYP3A4 inhibitor: raises simvastatin/lovastatin and carbamazepine levels and increases warfarin's effect
  • Additive QT risk

Counseling points

  • Take with food if it upsets the stomach
  • Report muscle pain if you also take a statin
  • Complete the full course
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