Allopurinol
Brand: Zyloprim
Key warning
Caution: rare but serious skin reactions; stop and report any rash
Common side effects
- Rash
- Nausea
- Gout flare when starting
- Drowsiness
- Diarrhea
Key interactions & cautions
- Raises levels of azathioprine and mercaptopurine
- May increase warfarin effect
- Caution with ampicillin (rash)
- Alcohol reduces its effect
Counseling points
- Take after meals to reduce stomach upset
- Drink plenty of water
- Does not treat an active gout attack
- Stop and report any skin rash
- Keep taking even during a flare
High-yield study aid for exam prep — not a substitute for the package insert or a pharmacist’s dispensing reference.