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Topiramate

Brand: Topamax

AnticonvulsantUsed for: Seizures, migraine preventionCNS & Psychiatric

No boxed warning on the current FDA label.

Caution
Acute angle-closure glaucoma (sudden vision change or eye pain), kidney stones, and metabolic acidosis.
Pregnancy
Avoid if possible: cleft lip and palate risk; also lowers contraceptive effectiveness.

Common side effects

  • Tingling in hands and feet
  • Drowsiness
  • Difficulty concentrating
  • Weight loss
  • Dizziness

Key interactions

  • May reduce birth-control effectiveness
  • Alcohol increases sedation
  • Adds to other sedating drugs
  • Caution with other seizure medicines

Counseling points

  • Drink plenty of water to reduce kidney stones
  • Report vision changes or eye pain
  • Do not stop suddenly
  • May cause word-finding difficulty
  • Use backup contraception if advised
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