Sulfamethoxazole/trimethoprim
Brand: Bactrim, Septra
Key warning
Caution: rare but serious skin and blood reactions
Common side effects
- Nausea
- Rash
- Elevated potassium
- Sun sensitivity
- Diarrhea
Key interactions & cautions
- May increase warfarin bleeding risk
- May raise potassium with ACE inhibitors or ARBs
- May raise methotrexate toxicity
- Caution with certain diabetes drugs
Counseling points
- Drink plenty of water
- Finish the full course
- Use sunscreen for sun sensitivity
- Report rash, blisters, or peeling skin
- Avoid if sulfa allergy
High-yield study aid for exam prep — not a substitute for the package insert or a pharmacist’s dispensing reference.