← Drug quick-reference

Sitagliptin

Brand: Januvia

DPP-4 inhibitorUsed for: Type 2 diabetesEndocrine & Diabetes

No boxed warning on the current FDA label. On the ISMP high-alert list.

Caution
Pancreatitis, severe joint pain, and bullous pemphigoid; dose reduced in kidney impairment.

Common side effects

  • Headache
  • Stuffy or runny nose
  • Upper respiratory infection
  • Joint pain
  • Nausea

Key interactions

  • Adds low blood sugar risk with sulfonylureas
  • Adds low blood sugar risk with insulin

Counseling points

  • May be taken with or without food
  • Report severe or persistent stomach pain
  • Report signs of allergic reaction or blisters
  • Continue diet and exercise
  • Monitor blood sugar as directed
  • Dose is lowered in kidney impairment
We ask 7 questions about Sitagliptin.Practice Sitagliptin →Test yourself on medications like Sitagliptin.Practice Medications →

High-yield study aid for exam prep, not a substitute for the package insert or a pharmacist’s dispensing reference.