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Prednisone

Brand: Deltasone (discontinued; Rayos is the only marketed brand)

CorticosteroidUsed for: Inflammation, immune suppressionEndocrine & Diabetes

No boxed warning on the current FDA label.

Caution
Adrenal suppression: taper after more than about 2 weeks; raises blood sugar, blood pressure, and infection risk.

Common side effects

  • Increased appetite
  • Trouble sleeping
  • Mood changes
  • Elevated blood sugar
  • Fluid retention

Key interactions

  • NSAIDs raise stomach ulcer risk
  • May raise blood sugar with diabetes drugs
  • Live vaccines should be avoided
  • May lower potassium with diuretics

Counseling points

  • Take with food to reduce stomach upset
  • Do not stop suddenly; taper as directed
  • Take in the morning
  • Report signs of infection
  • May raise blood sugar and blood pressure
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