Metronidazole
Brand: Flagyl
Boxed warning
Carcinogenic in mice and rats; avoid unnecessary use and reserve for approved indications.
- Caution
- Disulfiram-like reaction with alcohol during and for 3 days after treatment; peripheral neuropathy with prolonged use.
- Pregnancy
- Avoid in the first trimester when possible.
Common side effects
- Metallic taste
- Nausea
- Headache
- Dark urine
- Dizziness
Key interactions
- Avoid alcohol during and after treatment
- May increase warfarin effect
- Can interact with lithium
Counseling points
- Avoid alcohol during and 3 days after finishing
- Finish the full course
- Take with food to reduce upset stomach
- Urine may darken; this is harmless
- Report numbness or tingling in hands or feet
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High-yield study aid for exam prep, not a substitute for the package insert or a pharmacist’s dispensing reference.