Loperamide
Brand: Imodium
Boxed warning
Prescription capsules: torsades de pointes, cardiac arrest, and death at higher-than-recommended doses (often from misuse), and contraindicated under age 2; OTC Imodium carries no boxed warning.
- Caution
- Not for bloody diarrhea or diarrhea with fever; stop if no improvement in 48 hours.
Common side effects
- Constipation
- Dizziness
- Stomach cramps
- Dry mouth
- Nausea
Key interactions
- Avoid other QT-prolonging drugs
- Certain drugs raise its levels (interacting inhibitors)
- Adds drowsiness with sedatives
Counseling points
- Do not exceed the recommended dose
- Stop and seek care for bloody stools or fever
- Stay hydrated
- Not for diarrhea lasting beyond a couple days
- Report irregular heartbeat or fainting
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