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Latanoprost

Brand: Xalatan

Prostaglandin analog eye dropUsed for: Glaucoma, ocular hypertensionOther High-Yield

No boxed warning on the current FDA label.

Caution
Permanent iris darkening, eyelash growth, and darkening of the eyelid skin.
Storage
Unopened bottles refrigerated (36 to 46 F); once opened, room temperature for up to 6 weeks; protect from light.

Common side effects

  • Permanent darkening of the iris
  • Longer, darker eyelashes
  • Eye redness and stinging
  • Darkening of the eyelid skin

Key interactions

  • Separate other eye drops by at least 5 minutes

Counseling points

  • Usually instilled once daily in the evening
  • Iris color change can be permanent, especially in mixed-color eyes
  • Remove contact lenses and wait 15 minutes before reinserting
  • Unopened bottles are refrigerated; once opened, room temperature for 6 weeks
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