Lamotrigine
Brand: Lamictal
Boxed warning
Serious rashes including Stevens-Johnson syndrome and toxic epidermal necrolysis; stop at the first sign of rash.
- Caution
- Rash risk rises with rapid dose increases and with valproate; follow the slow titration schedule.
Common side effects
- Rash
- Dizziness
- Headache
- Blurred or double vision
- Nausea
Key interactions
- Valproate raises its levels and rash risk
- Some estrogen contraceptives lower its levels
- Certain seizure drugs speed its breakdown
Counseling points
- Report any new rash right away
- Follow the slow dose-increase schedule
- Do not stop suddenly
- Take at the same time each day
- Do not skip doses
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