Epinephrine
Brand: EpiPen, Auvi-Q, Adrenalin
No boxed warning on the current FDA label. On the ISMP high-alert list.
- Caution
- Anaphylaxis is treated with the 1 mg/mL product given intramuscularly into the thigh; the 0.1 mg/mL product is the IV strength, and confusing the two is a 10-fold error.
- Storage
- Room temperature, protected from light; replace the auto-injector if the solution is discolored or expired.
Common side effects
- Fast, pounding heartbeat
- Tremor and anxiety
- Pallor and dizziness
- Headache
Key interactions
- Beta blockers can blunt its effect
- Additive effects with other stimulants
- Tricyclics and MAO inhibitors intensify its cardiac effects
Counseling points
- Inject into the outer thigh: through clothing if needed
- Call 911 immediately after; a second reaction can follow hours later
- Do not inject into a vein, buttock, hand, or foot
- Check the expiry and the solution: discard if discolored
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High-yield study aid for exam prep, not a substitute for the package insert or a pharmacist’s dispensing reference.