Empagliflozin
Brand: Jardiance
No boxed warning on the current FDA label. On the ISMP high-alert list.
- Caution
- Ketoacidosis (sometimes with near-normal glucose), genital yeast infections, Fournier gangrene, and volume depletion.
- Pregnancy
- Not recommended in the second and third trimesters: fetal kidney effects.
Common side effects
- Genital yeast infections
- Urinary tract infections
- Increased urination
- Dehydration
- Low blood pressure
Key interactions
- Diuretics add to fluid loss
- Low-sugar risk rises with insulin or sulfonylureas
- Caution with blood-pressure drugs
Counseling points
- Take in the morning
- Stay well hydrated
- Report genital pain, redness, or swelling
- Practice good genital hygiene
- Report symptoms of ketoacidosis like deep breathing
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High-yield study aid for exam prep, not a substitute for the package insert or a pharmacist’s dispensing reference.