Dapagliflozin
Brand: Farxiga
No boxed warning on the current FDA label. On the ISMP high-alert list.
- Caution
- Ketoacidosis, genital yeast infections, Fournier gangrene, and volume depletion; held before major surgery.
- Pregnancy
- Not recommended in the second and third trimesters: fetal kidney effects.
Common side effects
- Genital yeast infections
- Urinary tract infections
- Increased urination
- Dehydration
Key interactions
- Additive low blood sugar with insulin or sulfonylureas
- Diuretics add to fluid loss
Counseling points
- Drink enough fluid
- Genital yeast infection is the signature side effect: report itching or discharge
- Report severe genital pain or swelling urgently
- The prescriber will usually hold it for at least 3 days before scheduled surgery
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High-yield study aid for exam prep, not a substitute for the package insert or a pharmacist’s dispensing reference.