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Bupropion

Brand: Wellbutrin

Atypical antidepressantUsed for: Depression, smoking cessationCNS & Psychiatric
Key warning

Boxed warning: suicidal thoughts and behaviors in children, adolescents, and young adults

Common side effects

  • Insomnia
  • Dry mouth
  • Headache
  • Weight loss
  • Agitation

Key interactions & cautions

  • Lowers seizure threshold with certain drugs
  • Avoid MAO inhibitors
  • Avoid abrupt alcohol reduction
  • Caution with other bupropion products

Counseling points

  • Take earlier in day to reduce insomnia
  • Do not crush extended-release tablets
  • Avoid if history of seizures or eating disorder
  • Report worsening mood or suicidal thoughts
  • Do not double up with smoking-cessation versions

High-yield study aid for exam prep — not a substitute for the package insert or a pharmacist’s dispensing reference.