← Drug quick-reference

Verapamil

Brand: Verelan (Calan discontinued)

Calcium channel blocker (non-dihydropyridine)Used for: High blood pressure, angina, rate controlCardiovascular

No boxed warning on the current FDA label.

Caution
Contraindicated in severe left ventricular dysfunction, cardiogenic shock, and heart block without a pacemaker.

Common side effects

  • Constipation
  • Swelling of ankles
  • Slow heartbeat
  • Dizziness

Key interactions

  • Raises digoxin levels
  • Additive slowing with beta blockers
  • Grapefruit juice raises its level
  • Raises statin levels

Counseling points

  • Constipation is common: fluids and fiber help
  • Do not crush extended-release tablets
  • Rise slowly to reduce dizziness
  • Report a very slow pulse
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