Tadalafil
Brand: Cialis
No boxed warning on the current FDA label.
- Caution
- Contraindicated with nitrates in any form; effects last up to 36 hours.
Common side effects
- Headache
- Flushing
- Back pain
- Indigestion
Key interactions
- Absolutely contraindicated with nitrates in any form
- Alpha blockers add to blood-pressure lowering
- Strong CYP3A4 inhibitors raise its level
Counseling points
- Never take with nitroglycerin or any nitrate, even occasional use
- Longer-acting than sildenafil: up to 36 hours
- Seek care for an erection lasting over 4 hours
- Report sudden vision or hearing loss
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