Promethazine
Brand: Phenergan
Key warning
Boxed warning: fatal respiratory depression in children under 2 — contraindicated in that age group. (The separate INJECTABLE form carries its own boxed warning for severe tissue injury including gangrene; that one is not part of the oral labeling.)
Common side effects
- Drowsiness
- Dry mouth
- Dizziness
- Low blood pressure
- Blurred vision
Key interactions & cautions
- Alcohol increases sedation
- Adds to other sedating drugs
- Adds to opioid sedation
Counseling points
- May cause marked drowsiness
- Do not drive until you know its effect
- Avoid alcohol
- Report muscle stiffness or high fever
- Rise slowly to reduce dizziness
High-yield study aid for exam prep — not a substitute for the package insert or a pharmacist’s dispensing reference.