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Montelukast

Brand: Singulair

Leukotriene modifierUsed for: Asthma, allergiesRespiratory & Allergy
Boxed warning

Serious neuropsychiatric events including agitation, depression, sleep disturbance, and suicidal thoughts; reserve for allergic rhinitis only when other treatments fail.

Caution
Not for acute asthma attacks.

Common side effects

  • Headache
  • Stomach upset
  • Cough
  • Mood changes
  • Fatigue

Key interactions

  • Some seizure drugs may lower its levels
  • Phenobarbital and rifampin may lower its levels

Counseling points

  • Take in the evening
  • Not for sudden asthma attacks
  • Keep a rescue inhaler available
  • Report mood or behavior changes
  • Take daily even when feeling well
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