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Lorazepam

Brand: Ativan

Benzodiazepine (C-IV)Used for: Anxiety, seizuresCNS & Psychiatric
Boxed warning · ISMP high-alert drug

Profound sedation, respiratory depression, coma, and death when combined with opioids; abuse, misuse, addiction, and withdrawal reactions on abrupt stopping.

Caution
Falls and confusion in older adults; respiratory depression with other CNS depressants.
Storage
Injection and oral concentrate require refrigeration; tablets at room temperature.
Pregnancy
Avoid if possible: neonatal sedation and withdrawal, especially with late-pregnancy use.

Common side effects

  • Drowsiness
  • Dizziness
  • Unsteadiness
  • Confusion

Key interactions

  • Dangerous sedation with opioids
  • Adds to alcohol and other sedatives
  • Avoid combining with other CNS depressants

Counseling points

  • May impair driving until you know its effect
  • Avoid alcohol
  • Do not stop suddenly
  • Controlled substance, do not share
  • Rise slowly to reduce falls
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High-yield study aid for exam prep, not a substitute for the package insert or a pharmacist’s dispensing reference.