← Drug quick-reference

Ibuprofen

Brand: Advil, Motrin

NSAIDUsed for: Pain, inflammation, feverPain & Inflammation
Boxed warning

Serious cardiovascular thrombotic events (heart attack and stroke) and serious GI bleeding, ulceration, and perforation; contraindicated for pain around CABG surgery (prescription labeling).

Caution
GI bleeding, kidney injury, and raised blood pressure; OTC labels carry no box but the same risks.
Pregnancy
Avoid from 20 weeks on: fetal kidney problems and low amniotic fluid, and ductus arteriosus closure after 30 weeks.

Common side effects

  • Stomach upset
  • Heartburn
  • Risk of stomach ulcer or bleeding
  • Elevated blood pressure
  • Fluid retention

Key interactions

  • Blunts blood pressure medicine effects
  • Raises bleeding risk with blood thinners
  • Avoid combining with other NSAIDs
  • May reduce aspirin heart protection

Counseling points

  • Take with food or milk
  • Use lowest dose for shortest time
  • Report black stools or stomach pain
  • Stay hydrated to protect kidneys
  • Avoid alcohol
We ask 14 questions about Ibuprofen.Practice Ibuprofen →Test yourself on medications like Ibuprofen.Practice Medications →
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High-yield study aid for exam prep, not a substitute for the package insert or a pharmacist’s dispensing reference.