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Fluticasone/salmeterol

Brand: Advair

Inhaled steroid + LABAUsed for: Asthma, COPDRespiratory & Allergy

No boxed warning on the current FDA label.

Caution
A controller, not a rescue inhaler; LABA monotherapy raises asthma death risk, which is why salmeterol is combined with a steroid here (the combination box was removed in 2017).

Common side effects

  • Hoarseness
  • Oral thrush
  • Throat irritation
  • Headache
  • Tremor

Key interactions

  • Strong CYP3A4 inhibitors raise steroid levels
  • Beta-blockers may reduce its effect
  • Caution with other QT or heart-rate drugs

Counseling points

  • Rinse mouth after each use
  • Use daily for control, not for sudden attacks
  • Keep a rescue inhaler for quick relief
  • Prime and clean the device as directed
  • Do not stop abruptly
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High-yield study aid for exam prep, not a substitute for the package insert or a pharmacist’s dispensing reference.