Ezetimibe
Brand: Zetia
No boxed warning on the current FDA label.
- Caution
- Liver enzyme elevation when combined with a statin; report unexplained muscle pain.
Common side effects
- Diarrhea
- Joint pain
- Fatigue
- Muscle aches
Key interactions
- Bile acid sequestrants reduce its absorption: separate the doses
- Additive muscle risk when combined with a statin
Counseling points
- Can be taken with or without food, at any time of day
- Often added to a statin rather than replacing it
- Report unexplained muscle pain
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