Dextromethorphan
Brand: Delsym, the DM in cough syrups
No boxed warning on the current FDA label.
- Caution
- Contraindicated with MAO inhibitors; abused at high doses for dissociative effects, so many states restrict sales to adults.
Common side effects
- Drowsiness
- Dizziness
- Nausea
- Confusion at high doses
Key interactions
- Contraindicated with MAO inhibitors
- Serotonin syndrome risk with SSRIs and SNRIs
- Additive sedation with alcohol
Counseling points
- For a dry, non-productive cough, not for a chesty, productive one
- Do not exceed the labeled dose; it is abused at high doses
- Check combination cold products so it is not doubled
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High-yield study aid for exam prep, not a substitute for the package insert or a pharmacist’s dispensing reference.