Bismuth subsalicylate
Brand: Pepto-Bismol, Kaopectate
No boxed warning on the current FDA label.
- Caution
- Contains a salicylate: Reye syndrome risk in children and teens with a viral illness; black stool and tongue are harmless.
Common side effects
- Harmless black stool
- Harmless black tongue
- Constipation
- Ringing in the ears at high doses
Key interactions
- Additive bleeding risk with anticoagulants: it is a salicylate
- Reduces absorption of tetracyclines
Counseling points
- Black stool and tongue are expected and harmless
- Do not give to children or teens with a viral illness
- Tell the pharmacist if you take a blood thinner
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